Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00484 |
SHMT1 Protein, Human, Recombinant (His)
Serine Methylase,Glycine Hydroxymethyltransfera... |
Human | HEK293 Cells |
Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to ... |